What question did this study set out to answer?

The aim is to explore how ATP influences protein condensation and migration in crowded environments.

February 19, 2026

Protein migration via dissolution of ATP-stabilized condensate in a gradient of AMP

Key Points

The aim is to explore how ATP influences protein condensation and migration in crowded environments.
Utilized bovine serum albumin (BSA) as a model protein.
Investigated the effects of ATP and AMP on protein behavior.
Conducted experiments in macromolecularly crowded environments.
BSA demonstrated an increased tendency to form condensates in ATP's presence.
AMP gradients promoted the migration of ATP-stabilized condensates.
Findings suggest a dynamic interaction between ATP and AMP affecting protein behavior.

Abstract

Herein, we report that the condensate-forming tendency of bovine serum albumin (BSA) increases in the presence of adenosine triphosphate (ATP) in macromolecularly crowded media. However, in the presence of adenosine...

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Cite This Study

. et al. (Thu,) studied this question.

synapsesocial.com/papers/6996a798ecb39a600b3ed6bc https://doi.org/https://doi.org/10.1039/d5cc07323e

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