Background: Cervical cancer is a significant health issue globally, with human papillomavirus (HPV) being the primary etiological factor. In Saudi Arabia, HPV prevalence and public awareness of its vaccination vary significantly across regions. Objectives: This review aims to synthesize existing research on HPV prevalence, genetic diversity, and public awareness in Saudi Arabia, identifying key findings and gaps to inform future public health interventions. Materials and Methods: We conducted a comprehensive narrative review using databases such as Google Scholar, Web of Science, PubMed, and Saudi Digital Library. Studies published between 2000 and 2024 focusing on HPV prevalence, genotypes, and public awareness in Saudi Arabia were included. Data extraction and quality assessment were performed independently by two reviewers. Results: A total of 93 studies met the inclusion criteria. HPV prevalence in Saudi Arabia ranged from 11% to 17%, with HPV-16, HPV-18, and HPV-45 being the most common genotypes. Public awareness of HPV and its vaccine was generally low, with significant regional variations. Barriers to vaccination included misinformation, accessibility, and safety concerns. Among healthcare providers and students, significant knowledge gaps and low vaccination rates were noted. Conclusion: The findings highlight the need for comprehensive public health strategies, including educational campaigns, regular screening programs, and enhanced training for healthcare providers. Addressing these areas can significantly reduce the burden of HPV-related diseases and improve health outcomes in Saudi Arabia.
Isameldin Elamin Medani (Tue,) studied this question.