What question did this study set out to answer?

The aim is to evaluate the effectiveness and safety of transperineal laser ablation for treating lower urinary tract symptoms related to benign prostate enlargement.

February 26, 2026

Transperineal Laser Ablation for Treatment of Lower Urinary Tract Symptoms in Benign Prostate Enlargement: A Systematic Review and Meta-analysis.

Key Points

The aim is to evaluate the effectiveness and safety of transperineal laser ablation for treating lower urinary tract symptoms related to benign prostate enlargement.
Conducted a systematic review and meta-analysis.
Included studies assessing transperineal laser ablation outcomes.
Compared results to traditional TURP methods.
Transperineal laser ablation showed better ejaculatory function preservation compared to TURP.
Patients experienced reduced operation time and shorter hospital stays.
Most evidence currently consists of retrospective studies with limited follow-up.

Abstract

TPLA demonstrated favorable outcomes for BPE without a negative impact on sexual function. This minimally invasive treatment was found to have advantages over TURP, such as, ejaculatory function preservation, reduced operative time, and shorter hospital stay. Evidence for this MIST is emerging but remains predominantly retrospective with short follow-up, highlighting the need for further comparative prospective studies.

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Cite This Study

Pires et al. (Fri,) studied this question.

synapsesocial.com/papers/699fe3d995ddcd3a253e7dd2 https://doi.org/https://doi.org/10.1590/s1677-5538.ibju.2025.0423

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