Uncomplicated urinary tract infections can cause significant physical and emotional burden for patients, with high rates of recurrence. The challenges of treating uncomplicated urinary tract infections are exacerbated by rising antimicrobial resistance in key uropathogens, primarily Escherichia coli, on a global scale. Clinicians should consider drug, pathogen, and host-related factors when selecting the most appropriate therapy.
Cantón et al. (Wed,) studied this question.