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November 8, 2019Open Access

Glucose 6-Phosphate Accumulates via Phosphoglucose Isomerase Inhibition in Heart Muscle

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Abstract

The reduction of PGI activity directly affects myocyte growth by regulating mTOR activation.

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Glucose 6-Phosphate Accumulates via Phosphoglucose Isomerase Inhibition in Heart Muscle | Synapse

Cite This Study

Karlstaedt et al. (Fri,) studied this question.

synapsesocial.com/papers/69a1748e6324c3a71a0ae6dd https://doi.org/https://doi.org/10.1161/circresaha.119.315180

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1A Computational Model Integrating Electrophysiology, Contraction, and Mitochondrial Bioenergetics in the Ventricular Myocyte2006 · 210 citations
2The enzymatic activity of phosphoglucose isomerase is not required for its cytokine function2002 · 26 citations
3Isolation and Culture of Adult Mouse Cardiac Myocytes2006 · 343 citations
4Mammalian Target of Rapamycin (mTOR) Inhibition with Rapamycin Improves Cardiac Function in Type 2 Diabetic Mice2013 · 151 citations
5Hematologically Important Mutations: Molecular Abnormalities of Glucose Phosphate Isomerase Deficiency1996 · 5 citations