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MT1B overexpression enhances malignancy of non-small cell lung cancer cells | Synapse

February 28, 2026Open Access

MT1B overexpression enhances malignancy of non-small cell lung cancer cells

Key Points

The research aims to investigate the role of MT1B overexpression in the malignancy of non-small cell lung cancer.
Experimental design examining cell lines with manipulated MT1B expression
Assessment of cell growth and invasion capabilities
Analysis of tumor progression indicators
MT1B overexpression correlated with increased cell growth and invasion
Enhanced malignancy was observed in tumor models due to MT1B
Findings suggest that targeting MT1B may inhibit lung cancer progression

Abstract

Yoon Hee Park, Hong Lee, Haewon Kim, Hayan Park, Su A Park, Jin Young Choi, Chaewon Park, Yoon Jeong Nam, Hyejin Lee, Yu-Seon Lee, Jaeyoung Kim, Byoungcheun Lee, Hye-Jin Kim, Ju-Han Lee 59:161-8. https://doi.org/10.5483/BMBRep.2025-0186

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Cite This Study

Park et al. (Thu,) studied this question.

synapsesocial.com/papers/69a285da0a974eb0d3c00cf4 https://doi.org/https://doi.org/10.5483/bmbrep.2025-0186