Cardiac Troponin T molecules in ESRD patients are smaller (<18 kDa) than those in AMI patients, which could inform the development of more specific diagnostic immunoassays.
We found that cTnT forms in ESRD patients are small (<18 kDa) and different from forms seen in AMI patients. These insights may prove useful for development of a more specific cTnT immunoassay, especially for the acute and diagnostic phase of myocardial infarction.
Mingels et al. (Tue,) studied this question.