Optimization and validation of an HPLC method for the quantification of Etodolac in liposomes and assessment of its pharmacokinetic profile. | Synapse
March 2, 2026
Optimization and validation of an HPLC method for the quantification of Etodolac in liposomes and assessment of its pharmacokinetic profile.
Key Points
To optimize and validate an HPLC method for quantifying etodolac, particularly in liposomes, and assess its pharmacokinetic profile.
Developed an HPLC method for etodolac analysis.
Validated the method for routine quantitative analysis.
Applied the method to measure etodolac in bulk and liposomes.
The HPLC method accurately quantified etodolac in various forms.
Successful validation supports use in routine analyses of etodolac in liposomes.
Abstract
Conclusions: The developed and validated method of HPLC was successfully applied to determine Etodolac in bulk and liposomes for routine quantitative analysis.