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N4BP1 promotes the progression of acute glaucoma by promoting pyroptosis through the JAK2/STAT3 pathway | Synapse
March 3, 2026
N4BP1 promotes the progression of acute glaucoma by promoting pyroptosis through the JAK2/STAT3 pathway
NJ
Nan Jiang
JZ
Jie Zhu
JZ
Jin Zhou
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Key Points
N4BP1 promotes pyroptosis in acute glaucoma, influencing disease progression strongly.
Key evidence shows a significant increase in pyroptosis markers linked to N4BP1 levels.
Observational analysis reveals that alterations in JAK2/STAT3 signaling impact cell death processes.
This finding suggests potential therapeutic avenues for managing acute glaucoma through cellular intervention.
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Jiang et al. (Wed,) studied this question.
synapsesocial.com/papers/69a75a79c6e9836116a20557
https://doi.org/https://doi.org/10.1016/j.exer.2026.110896
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