Enhanced antiproliferative and anti-inflammatory effects of combined metformin, tadalafil, and tamsulosin in a rat model of testosterone-induced benign prostatic hyperplasia
Key Points
The combined treatment demonstrates strong antiproliferative and anti-inflammatory effects, improving outcomes in benign prostatic hyperplasia.
In the rat model, the combination resulted in a notable reduction of prostate gland size by about 40%.
This was an observational study utilizing a rat model of testosterone-induced benign prostatic hyperplasia.
The findings suggest that the combination therapy could lead to new treatment options, yet further studies in humans are needed.
Effets antiprolifératifs et anti-inflammatoires améliorés de la combinaison de la metformine, du tadalafil et du tamsulosine dans un modèle de rat de l'hyperplasie bénigne de la prostate induite par la testostérone | Synapse