Multi-omics analysis reveals that FABP2 suppresses colorectal cancer progression by regulating sphingomyelin metabolism via the PPAR signaling pathway | Synapse
March 3, 2026Open Access
Multi-omics analysis reveals that FABP2 suppresses colorectal cancer progression by regulating sphingomyelin metabolism via the PPAR signaling pathway
Key Points
FABP2 suppresses colorectal cancer progression by regulating sphingomyelin metabolism—an important pathway.
The analysis showed a notable decrease in tumoral sphingomyelin in response to FABP2 modulation, influencing cancer signaling.
Observational analysis utilized multi-omics techniques to study metabolic changes linked to FABP2 and PPAR pathway.
Findings support the potential for targeting FABP2 in colorectal cancer therapies, indicating novel intervention strategies.