The possible role of sirtuins and MiRNAs in gastrointestinal cancers: special focus on Sirt1 | Synapse
March 3, 2026Open Access
The possible role of sirtuins and MiRNAs in gastrointestinal cancers: special focus on Sirt1
Key Points
Sirt1 and specific miRNAs influence oncogenes and tumor suppression in gastrointestinal cancers, particularly highlighting intricate molecular pathways.
Key findings include that alterations in sirtuins and miRNAs can affect cancer progression metrics, emphasizing their potential as therapeutic targets.
Observational analysis identifies the involvement of Sirt1 in multiple gastrointestinal cancer types, linking sirtuins with significant molecular pathways.
Understanding these interactions may enable new strategies for treatment in gastrointestinal cancers, calling for further exploration in clinical settings.