March 3, 2026Open Access

Genomic epidemiology of extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae in Mwanza, Tanzania

Key Points

The predominance of ESBL-EC ST131 indicates a high-risk virulent clone.
First report of clonal cluster ESBL-KP ST2390 in the region emphasizes emerging threats.
Genomic epidemiology methods reveal significant clonal diversity among isolates.
Reinforced infection control strategies are critical to manage the spread of these infections.

Abstract

This study highlights clonal clusters, the first report of ESBL-KP ST2390, and the predominance of the virulent high-risk clone ESBL-EC ST131 in Mwanza, Tanzania. Underscoring the critical need for reinforced infection control strategies and genomic surveillance.

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Cite This Study

Silago et al. (Tue,) studied this question.

synapsesocial.com/papers/69a75afec6e9836116a2185b https://doi.org/https://doi.org/10.1016/j.jgar.2026.01.010

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