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Mechanisms of Chemoresistance in Malignant Pleural Mesothelioma: The Regulatory Role of miRNAs | Synapse
March 3, 2026
Mechanisms of Chemoresistance in Malignant Pleural Mesothelioma: The Regulatory Role of miRNAs
AM
Andrea Martinez-Marroquin
JG
Javier Gaytán-Cervantes
HR
Haydeé Rosas-Vargas
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Key Points
Chemoresistance is driven by specific miRNAs, emphasizing their regulatory role in treatment failure.
Key findings suggest that miRNAs serve as vital biomarkers for understanding resistance mechanisms.
Observational analysis highlights the interaction between miRNAs and cellular pathways that contribute to chemoresistance.
Future studies may enable targeted therapies based on miRNA profiles in malignant pleural mesothelioma.
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Martinez-Marroquin et al. (Tue,) studied this question.
synapsesocial.com/papers/69a75b4ac6e9836116a22611
https://doi.org/https://doi.org/10.1016/j.arcmed.2025.103326