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March 3, 2026
Open Access
Protein Tyrosine Phosphatases in Schizophrenia: A Review of Pathophysiology and Emerging Evidence
KM
Karthika Murugesan
University of North Texas
DR
Delvy Rebellow
Malankara Orthodox Syrian Church Medical College Hospital
AK
Alousious Kasagga
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Key Points
Schizophrenia may be linked to protein tyrosine phosphatase activity, impacting neurotransmission processes.
Evidence highlights specific biomarkers associated with protein tyrosine phosphatase dysfunction in schizophrenia.
Review encompasses pathophysiological mechanisms involving protein tyrosine phosphatases in psychiatric disorders.
Potential interventions targeting these enzymes could lead to innovative treatment approaches for schizophrenia.
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Protein Tyrosine Phosphatases in Schizophrenia: A Review of Pathophysiology and Emerging Evidence | Synapse
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Murugesan et al. (Tue,) studied this question.
synapsesocial.com/papers/69a75b5dc6e9836116a22946
https://doi.org/https://doi.org/10.7759/cureus.102418