Proteomic footprint of serum urate concentration and urate transporter ABCG2 dysfunctional polymorphism: a cross-sectional study

Key Points

• Elevated serum urate concentration is linked to ABCG2 dysfunctional polymorphism, indicating genetic influence on urate levels.
• Analysis shows a significant association between serum urate concentration and ABCG2 genotypes across various participants.
• Cross-sectional analysis includes diverse demographic data, focusing on the role of proteomic changes in urate metabolism.
• Results highlight potential genetic factors influencing urate levels, emphasizing the need for further genetic validation studies.