Transgenerational response to the ingestion of an endocrine disruptor: phenotypic, genetic, and epigenetic analyses in quail

Key Points

• Phenotypic changes were observed in quail across generations, indicating a transgenerational response to endocrine disruptors.
• Genetic analysis revealed significant alterations in gene expression linked to endocrine disruptor exposure over generations.
• Epigenetic analysis suggested heritable changes that may influence future generations of quail exposed to these substances.
• The study highlights the potential long-term effects of endocrine disruptors on wildlife, calling for further research into environmental impacts.