Coagulation-related genes COL3A1 and MMP1 influence the development of osteoarthritis and the surrounding immunological environment

Key Points

• Osteoarthritis subtypes are influenced by coagulation-related genes, impacting disease progression.
• Key findings show that COL3A1 regulates chondrocyte behavior in inflammatory environments.
• Analysis highlights the significance of coagulation pathways in osteoarthritis development.
• Findings suggest new strategies for osteoarthritis management based on these molecular insights.