March 3, 2026Open Access

Impact of Power Morcellation and Histopathological Subtypes on the Development of Peritoneal Leiomyomatosis Following Laparoscopic Myomectomy

Key Points

Peritoneal leiomyomatosis occurs more frequently with unconfined morcellation than confined methods, indicating a significant surgical risk.
Patients diagnosed with cellular leiomyoma require long-term follow-up due to the potential for severe complications, especially after unconfined morcellation.
Histopathological subtype classification aids in assessing risk for developing peritoneal leiomyomatosis after laparoscopic myomectomy.
Adopting confined morcellation techniques could potentially reduce the incidence of this rare but serious complication.

Abstract

Peritoneal leiomyomatosis is a rare complication of laparoscopic myomectomy and increased incidence after unconfined morcellation is a serious concern. Confined (in-bag) morcellation appears to reduce the risk of peritoneal leiomyomatosis and should be the standard of care. Diagnosis of myomas as cellular leiomyoma subtype on histopathology merits high clinical suspicion for possibility of subsequent peritoneal leiomyomatosis in patients with unconfined morcellation. Therefore, close and long-term follow-up of these patients is essential.

Impact of Power Morcellation and Histopathological Subtypes on the Development of Peritoneal Leiomyomatosis Following Laparoscopic Myomectomy

Key Points

Abstract

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