What does this research mean for the field?

Pre-existing depression in patients referred for TAVR is associated with an increased risk of unplanned rehospitalization after the procedure, though it does not impact wait time-related outcomes. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

March 3, 2026Open Access

Impact of depression on TAVR wait time and post-TAVR outcomes: a population-based study

Key Points

Depression is associated with unplanned rehospitalization after TAVR, highlighting a significant concern for patient outcomes.
Approximately 33% of patients referred for TAVR have pre-existing depression, emphasizing its prevalence in this population.

Structured PICO

Does pre-existing depression impact wait time-related outcomes or unplanned rehospitalization in patients referred for TAVR?

Population

Patients referred for transcatheter aortic valve replacement (TAVR)

Intervention

Pre-existing depression (exposure)

Comparator

No pre-existing depression

Outcome

Wait time-related outcomes and unplanned rehospitalization after TAVRhard clinical

Pre-existing depression is common among TAVR candidates and serves as a risk factor for unplanned post-procedural rehospitalization.

Abstract

Nearly 1 in 3 patients referred for TAVR have pre-existing depression. While depression does not impact wait time-related outcomes, it is associated with unplanned rehospitalization after TAVR.

Impact of depression on TAVR wait time and post-TAVR outcomes: a population-based study

Key Points

Structured PICO

Abstract

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