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Novel C-terminal HBx truncation (G135) in genotype D1 HBV: predicted effects on oncogenic signaling | Synapse
March 3, 2026
Open Access
Novel C-terminal HBx truncation (G135) in genotype D1 HBV: predicted effects on oncogenic signaling
KJ
Kamyar Mazloum Jalali
HM
Hamidreza Mollaei
CK
Chiman Karami
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Key Points
The HBx truncation G135 is predicted to disrupt oncogenic signaling pathways.
This study identifies significant alterations in tumor biomarkers linked to genotype D1 HBV.
Predictions were made using bioinformatics tools to analyze molecular interactions.
The findings highlight the need for further investigation into HBV's role in cancer development.
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Jalali et al. (Wed,) studied this question.
synapsesocial.com/papers/69a75c4ec6e9836116a250fe
https://doi.org/https://doi.org/10.1186/s13027-026-00730-1
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