March 3, 2026Open Access

Risk factors for lateral and skip lymph node metastasis in adolescents and young adults with papillary thyroid carcinoma

Key Points

Lateral lymph node metastasis is linked to tumors larger than 1.1 cm and three or more central lymph node metastases.
The analysis found that having five or fewer skip lymph node metastases is a risk factor for skip metastasis.
Assessment using tumor size and lymph node involvement highlighted critical indicators in tumor progression.
These findings may enable better risk stratification and treatment planning for young patients with thyroid cancer.

Abstract

This study demonstrated that the diameter of the largest tumor greater than 1.1 cm and a number of CLNM equal to or greater than 3 were independent risk factors for LLNM in AYAs with PTC. Additionally, a number of LLNM equal to or less than 5 was identified as a risk factor for SLNM.

Risk factors for lateral and skip lymph node metastasis in adolescents and young adults with papillary thyroid carcinoma

Key Points

Abstract

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