The stem of Schisandra chinensis and Schisandrin B alleviated DNCB-induced atopic dermatitis in mice by inhibiting the NF-κB pathway

Key Points

• Schisandra chinensis extract and Schisandrin B alleviate symptoms of atopic dermatitis, including skin barrier dysfunction and inflammation.
• The study reveals that activation of the NF-κB pathway is inhibited, promoting skin health in a mouse model.
• Therapeutic strategies involving Schisandra chinensis and Schisandrin B appear to disrupt the cycle of chronic atopic dermatitis effectively.
• These findings highlight the potential of botanical treatments in managing immune-related skin conditions.