G-quadruplex mediated DNA HCR amplification for ultra-sensitive photoelectrochemical sensing of miRNA-141

Key Points

• Ultra-sensitive photoelectrochemical sensing successfully detects miRNA-141, indicating effective amplification methods.
• Detection reaches a limit of 0.1 fM for miRNA-141, showing significant sensitivity enhancements.
• Utilizes G-quadruplex mediated DNA hybridization chain reaction for amplification and detection.
• Highlights potential applications in diagnostics and environmental monitoring, suggesting broader impacts on biotechnology.