March 3, 2026

Successful Treatment of Cutaneous Lupus Erythematosus in a Horse With Tacrolimus Ointment

Key Points

Clinical resolution of cutaneous lupus erythematosus occurred over 3 years with tacrolimus ointment.
Treatment also involved UV-blocking mask, preventing flare-ups from sunlight exposure.
Routine application of topical tacrolimus proved effective without adverse effects reported.
This finding supports the use of topical therapies for similar dermatological issues in equines.

Abstract

A 9-year-old gelding Quarter Horse with a lesion on the right upper eyelid was diagnosed with cutaneous lupus erythematosus. Clinical resolution and control of UV-induced flares were achieved with topical tacrolimus and a UV-blocking mask without adverse effects over the following 3 years.

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Dropsy et al. (Wed,) studied this question.

synapsesocial.com/papers/69a75d02c6e9836116a2663f — DOI: https://doi.org/10.1111/vde.70051

Also consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

Topical 0.1% Tacrolimus for the Treatment of Discoid Lupus Erythematosus and Pemphigus Erythematosus in Dogs· 2004 · 46 citations
Corticosteroids and Immune Suppressive Therapies in Horses· 2017 · 39 citations
Long‐term successful treatment of a donkey with cutaneous lupus erythematous with methotrexate· 2020 · 5 citations
A Randomized, Double-Blinded Placebo Controlled Crossover Study Evaluating 0.03% Tacrolimus Ointment Monotherapy in the Treatment of Discoid Lupus Erythematosus in Dogs· 2017 · 9 citations
Efficacy of tacrolimus 0.1% ointment in cutaneous lupus erythematosus: A multicenter, randomized, double-blind, vehicle-controlled trial· 2011 · 101 citations

Authors

Hélène Dropsy

École Nationale Vétérinaire d'Alfort

Jean‐Charles Husson

Frédérique Degorce‐Rubiales

Laboratoire d'Aérologie

Journals

Veterinary Dermatology

Actions

Institutions

Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement

École Nationale Vétérinaire d'Alfort

References and Citations

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Successful Treatment of Cutaneous Lupus Erythematosus in a Horse With Tacrolimus Ointment

Key Points

Abstract

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Discussion

Cite this study

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Authors

Journals

Actions

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References and Citations

Citation Network

Connected Papers

Discussion

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