Protein kinase-related tumors in the pediatric population

Key Points

• Protein kinase mutations significantly influence tumor aggressiveness and patient outcomes in the pediatric population.
• Among evaluated cases, a notable 35% of tumors expressed specific oncogenic biomarkers tied to protein kinases.
• Analysis of tumor samples focused on cell signaling pathways affecting therapeutic responses and resistance.
• These findings highlight the need for tailored treatment approaches in children with protein kinase-related tumors.