Factors associated with severity of pulmonary tuberculosis in people living with and without HIV: a systematic review

Key Points

• Severity of pulmonary tuberculosis is significantly affected by co-infection with HIV and immune response alterations.
• Data shows that individuals with HIV experience more severe tuberculosis cases, leading to higher mortality rates.
• This systematic review analyzes existing literature on pulmonary tuberculosis in the context of HIV co-infection across diverse populations.
• Findings indicate that understanding these factors may enhance targeted treatment strategies, improving overall patient care.