Pathological mechanisms of hepatic ischemia-reperfusion injury and stem cell–based therapeutic strategies: Mechanistic insights and translational perspectives

Key Points

• Hepatic ischemia-reperfusion injury leads to significant cellular damage and impaired liver function, impacting recovery.
• A focus on stem cell therapy indicates its potential to enhance liver repair and mitigate injury, showing promise for clinical applications.
• Mechanistic insights derived from various studies enhance understanding of pathological mechanisms in liver injury.
• Translational perspectives highlight the need for further clinical trials to validate stem cell approaches and improve outcomes.