METTL3-regulated m6A modification modulates autophagy of placental mesenchymal stem/stromal cell by YTHDF3-mediated degradation of LncRNA GAS5 in preeclampsia
Key Points
Autophagy alterations in placental mesenchymal stem cells affect preeclampsia outcomes, indicating a regulatory mechanism.
Key evidence shows an association between METTL3 activity and the stability of LncRNA GAS5 impacted by YTHDF3.
Analysis focused on RNA modifications and cellular processes in placental mesenchymal stem cells, linking m6A methylation to autophagy.
Understanding these molecular interactions may enable new therapeutic strategies for managing preeclampsia.
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METTL3-regulated m6A modification modulates autophagy of placental mesenchymal stem/stromal cell by YTHDF3-mediated degradation of LncRNA GAS5 in preeclampsia | Synapse