Single-cell transcriptomics and metabolomics demonstrate that Taohe Chengqi decoction alleviates sepsis-associated acute lung injury by modulating immunometabolism

Key Points

• The intervention alleviates acute lung injury in a sepsis model, indicating potential therapeutic benefits.
• Key metrics show significant modulation of immunometabolism through the treatment with Taohe Chengqi decoction.
• Single-cell transcriptomics and metabolomics were employed to analyze the cellular and metabolic changes associated with treatment.
• These findings highlight the importance of immunometabolism in treating sepsis-associated complications, warranting further research.