Membrane and co-culture engineering for high-level curcumin production in Escherichia coli

Key Points

• High-level curcumin production was achieved using engineered co-cultures, enhancing metabolic pathways.
• Quantitative analysis showed a significant increase in curcumin yield, reaching 2.5 g/L within 48 hours.
• Membrane engineering enabled optimized resource allocation among microorganism populations in the co-culture.
• Findings suggest improvements in curcumin production techniques for future biotechnological applications.