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March 3, 2026
Identification of STAT4 as a novel target linking immune-mediated diseases and Alzheimer's disease
QS
Qiaoyang Sun
LD
Lingwen Ding
ZZ
Zhiwei Zhang
Capital Medical University
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Key Points
STAT4 may serve as a crucial link, indicating its role in both Alzheimer's disease and immune-mediated diseases.
Elevation in biomarkers associated with STAT4 suggests a significant relationship with both conditions.
Assessment of immune responses reveals connections between immune-mediated diseases and Alzheimer's disease mechanisms.
Understanding STAT4's role calls for further exploration into potential therapeutic interventions through modulation.
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Sun et al. (Mon,) studied this question.
synapsesocial.com/papers/69a75e81c6e9836116a292ba
https://doi.org/https://doi.org/10.1016/j.jns.2025.124565
Identification de STAT4 comme une nouvelle cible liant les maladies médiées par le système immunitaire et la maladie d'Alzheimer | Synapse