A low dose is better than no dose: Is it time to consider lowering the US minimum plateletpheresis yield?

Key Points

• Lowering the minimum yield for plateletpheresis may improve blood availability, with implications for patient care.
• Current standards for yield are higher than necessary, leading to wasted resources and risks of shortages.
• Assessment of existing data indicates that a low dose can be more effective than no dose at all.
• Further evaluation is needed to understand the long-term impacts of changing the minimum yield on transfusions.