Metabolic crosstalk in the metastatic prostate cancer-bone microenvironment: mechanism, detection and therapeutic strategies

Key Points

• Metabolic crosstalk significantly alters the bone microenvironment, impacting metastatic prostate cancer progression and therapy.
• Key biomarkers related to this crosstalk were identified, providing potential targets for therapeutic strategies.
• This observational analysis evaluates various detection methods to monitor metabolic changes in prostate cancer metastasis.
• Findings may enhance treatment efficacy, though further studies will be needed to validate these strategies in clinical settings.