Role of human cytomegalovirus in the pathogenesis of periapical lesions – A systematic review and meta-analysis

Key Points

• Human cytomegalovirus significantly contributes to the pathogenesis of periapical lesions, highlighting its role.
• The meta-analysis indicates a clear association between the presence of human cytomegalovirus and greater lesion severity.
• Investigation through systematic review captured data from multiple studies examining viral impact on lesions.
• Findings imply a potential need for therapeutic strategies targeting human cytomegalovirus in dental health.