Ezrin (EZR) promotes breast cancer progression and drug resistance: Molecular mechanisms involving STAT3 activation

Key Points

• Breast cancer progression is linked to ezrin activation, leading to increased drug resistance.
• Key evidence shows that elevated ezrin correlates with STAT3 activation and poor patient outcomes.
• Analysis of molecular interactions highlights the role of ezrin in enhancing survival pathways in cancer cells.
• This finding suggests targeting ezrin may offer new strategies for overcoming drug resistance in breast cancer.