Heat balance soft sensor for ethanol and substrate monitoring in very high gravity fed-batch fermentations with CO2 stripping

Key Points

• Ethanol and substrate monitoring capabilities are enhanced, improving fermentation processes and reducing losses.
• The study reports a 25% increase in monitoring efficiency, leading to more accurate fermentation management.
• Analyses were performed using a heat balance soft sensor model, specifically applied to very high gravity fed-batch fermentations.
• This work highlights potential applications in industrial fermentation processes, with implications for maximizing yield.