Molecular epidemiology of Streptococcus pneumoniae serotypes 6A and 6B: A systematic review of circulating clones and clonal clusters

Key Points

• Streptococcus pneumoniae serotypes 6A and 6B show widespread genetic variation, affecting global health.
• Key evidence indicates that certain lineages possess dual serotypic characteristics, complicating epidemiological tracking.
• Systematic review identified circulating clones and clonal clusters, influencing antibiotic resistance patterns.
• These findings highlight the need for continuous monitoring to prevent the spread of invasive pneumococcal diseases.