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A role of FURIN in promoting TGF-β signaling activation in MAFLD: Evidence from UK Biobank proteomic cohort | Synapse
March 3, 2026
A role of FURIN in promoting TGF-β signaling activation in MAFLD: Evidence from UK Biobank proteomic cohort
HW
Hao Wang
General Cardiology
XL
Xingang Li
XX
Xiaoqian Xu
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Key Points
FURIN promotes TGF-β signaling activation, potentially contributing to MAFLD progression.
Key evidence shows significant proteomic changes linked to FURIN in the UK Biobank cohort.
Observational analysis across the UK Biobank reveals associations between FURIN levels and TGF-β activity.
Supports therapeutic exploration of FURIN as a target in treating MAFLD and related conditions.
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Wang et al. (Fri,) studied this question.
synapsesocial.com/papers/69a75f95c6e9836116a2b0bf
https://doi.org/https://doi.org/10.1016/j.ijbiomac.2026.150634
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