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Impact of a Multidisciplinary SAE Oversight Committee on CAR-T Toxicity Management: Clinical Outcomes and Provider Perceptions | Synapse
March 3, 2026
Impact of a Multidisciplinary SAE Oversight Committee on CAR-T Toxicity Management: Clinical Outcomes and Provider Perceptions
MT
Melinda Tan
MG
Malvika Gupta
MS
Monica Shaw
Mayo Clinic in Arizona
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Key Points
Multidisciplinary oversight enhances clinical outcomes related to CAR-T therapy management across various provider perceptions.
Clinical outcomes improved significantly, indicating effective toxicity management strategies for CAR-T patients.
Observational analysis assessed the role of a multidisciplinary oversight committee in managing CAR-T therapy complications and outcomes.
Findings support the need for multidisciplinary approaches, highlighting broader implications for CAR-T management in clinical settings.
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Tan et al. (Sun,) studied this question.
synapsesocial.com/papers/69a76081c6e9836116a2d4dd
https://doi.org/https://doi.org/10.1016/j.jtct.2025.12.262