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Induction Therapy Accelerates Immune Aging in Multiple Myeloma: Implications for Cellular Therapy Readiness | Synapse
March 3, 2026
Induction Therapy Accelerates Immune Aging in Multiple Myeloma: Implications for Cellular Therapy Readiness
EM
Ehsan Malek
Roswell Park Comprehensive Cancer Center
MD
Marco L. Davila
Roswell Park Comprehensive Cancer Center
BB
Brian C. Betts
Roswell Park Comprehensive Cancer Center
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Key Points
Accelerated immune aging occurs due to induction therapy, affecting treatment outcomes significantly.
The analysis reveals a strong correlation between induction therapy and changes in immune response metrics.
Assessment utilizes data from multiple myeloma cases, focusing on immune aging and its implications for therapy.
This finding highlights the need for careful consideration of immune aging in future cellular therapies.
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Cite This Study
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Malek et al. (Sun,) studied this question.
synapsesocial.com/papers/69a76081c6e9836116a2d501
https://doi.org/https://doi.org/10.1016/j.jtct.2025.12.218