Plasma neurofilament light chain in pediatric hereditary spastic paraplegia

Key Points

• Neurofilament light chain levels are associated with hereditary spastic paraplegia severity, indicating its relevance as a biomarker.
• The study reports significant findings on neurofilament levels in 20 pediatric patients with hereditary spastic paraplegia.
• Assessment of plasma samples reveals elevated levels of neurofilament light chain, highlighting its role in monitoring disease progression.
• Findings imply plasma neurofilament light chain may serve as a valuable tool for assessing neurological disorders in children.