Elevated branched-chain amino acids linked to hippocampal volumes and cognitive improvement in mild cognitive impairment

Key Points

• Cognitive improvement was evident, as indicated by increased hippocampal volumes.
• Participants with elevated branched-chain amino acids showed significant cognitive gains in this analysis.
• Observational analysis assessed the relationship between biomarker levels and cognitive performance over a period.
• Implications suggest branched-chain amino acids could be explored for therapeutic use in mild cognitive impairment.