High-glucosinolate Brassica rapa lines mitigate diet-induced hepatic steatosis through activation of the AMPK/SIRT1 and NRF2 pathways

Key Points

• Hepatic steatosis mitigation is linked to glucosinolate-rich diets, indicating a protective effect.
• Key evidence shows a significant activation of AMPK and SIRT1 pathways with glucosinolate consumption.
• Analysis indicates a dietary intervention approach through Brassica rapa to combat liver fat accumulation.
• Findings suggest further exploration of glucosinolates for therapeutic applications against metabolic disorders.