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Growth-coupled evolution accelerates efficient biosynthesis of natural products | Synapse
March 3, 2026
Growth-coupled evolution accelerates efficient biosynthesis of natural products
MC
Minjun Chang
KS
Kyubin Shim
YK
Yoo‐Sung Ko
Korea Advanced Institute of Science and Technology
Key Points
Efficient biosynthesis of natural products is significantly enhanced through growth-coupled evolution, optimizing resource use.
The research shows that implementing this evolutionary strategy can lead to better yields in producing valuable compounds.
Analysis of different biosynthetic pathways reveals the advantages and mechanisms of this growth-coupled approach.
This approach highlights the potential for increased productivity in natural product synthesis and its applicability in industrial settings.
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Chang et al. (Sun,) studied this question.
synapsesocial.com/papers/69a7615cc6e9836116a2f347
https://doi.org/https://doi.org/10.1016/j.tibtech.2025.12.007