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Transcranial direct current stimulation targeting dmPFC ameliorates somatic symptoms in depression: A randomized control trial | Synapse
March 3, 2026
Transcranial direct current stimulation targeting dmPFC ameliorates somatic symptoms in depression: A randomized control trial
TZ
Ting Zhang
YY
Yue Yu
Anhui Medical University
QL
Qianqian Li
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Key Points
Somatic symptoms in depression were significantly reduced after transcranial direct current stimulation intervention, suggesting efficacy.
A 20% decrease in somatic symptoms was noted post-treatment, based on standardized measures.
Randomized controlled trial design ensured robust evaluation of the effects of targeted stimulation on depressive symptoms.
This intervention may enable new treatment avenues for managing somatic aspects of depression.
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Zhang et al. (Tue,) studied this question.
synapsesocial.com/papers/69a7618bc6e9836116a2f8eb
https://doi.org/https://doi.org/10.1016/j.jad.2026.121413