Depth-specific changes in cortical T1w/T2w ratio are associated with impaired executive function in chronic schizophrenia

Key Points

• Impaired executive function correlates with changes in the cortical t1w/t2w ratio, highlighting brain imaging's role in schizophrenia.
• A significant correlation was observed between cortical depth and the t1w/t2w ratio, indicating specific brain alterations.
• Cortical brain imaging assessment highlights distinct patterns in individuals with chronic schizophrenia.
• The findings suggest that the t1w/t2w ratio may serve as a biomarker for cognitive impairments in schizophrenia.