Cathodic electrochemiluminescence biosensing based on In2Se3/Ag3PO4 composite for sensitive detection of p-Tau181 protein

Key Points

• Detection of p-Tau181 protein achieved with high sensitivity using the In2Se3/Ag3PO4 composite.
• The electrochemiluminescence biosensing method demonstrates a low detection limit of 0.55 pg/mL for p-Tau181.
• Composite design integrates In2Se3 and Ag3PO4 to enhance electrochemiluminescence properties effectively.
• This method supports early diagnosis of Alzheimer's disease biomarkers, allowing for better patient management.