March 3, 2026Open Access

Enhanced lateral flow immunoassay for point-of-care monitoring of sulfamethazine residues based on antibody labeled with Au/Ir@Cu/Zn-MOF signal amplification

Key Points

The developed assay shows remarkable sensitivity for sulfamethazine detection, enhancing food safety measures.
Detection limit reached as low as 0.1 ppb, indicating high efficiency of the nanocomposite used.
Analysis utilizing Au/Ir@Cu/Zn-MOF as a signal amplification probe reveals strong performance in environmental monitoring.
Findings highlight potential for broader applications in rapid testing, underscoring need for external validation.

Abstract

The Au/Ir@Cu/Zn-MOF nanocomposite utilized as signal amplification probe demonstrated remarkable sensitivity for the detection of SM2. The developed Au/Ir@Cu/Zn-MOF-based LFIA exhibits significant potential for the rapid and sensitive detection of contaminants in environmental monitoring and food safety.

Enhanced lateral flow immunoassay for point-of-care monitoring of sulfamethazine residues based on antibody labeled with Au/Ir@Cu/Zn-MOF signal amplification

Key Points

Abstract

Cite This Study