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From Skin to Brain Activation: Decoding Frictional Pain in Amputees Versus Healthy Individuals | Synapse
March 3, 2026
From Skin to Brain Activation: Decoding Frictional Pain in Amputees Versus Healthy Individuals
XF
Xingxing Fang
WT
Wei Tang
SZ
Shousheng Zhang
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Key Points
Frictional pain activates different neural pathways in amputees compared to healthy individuals.
Increased brain activation was observed in amputees when experiencing frictional pain, emphasizing altered sensory processing.
Observational analysis across diverse groups highlights the unique pain perceptions of amputees compared to healthy individuals.
Understanding these differences may enable better pain management strategies for amputees and improve their quality of life.
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Fang et al. (Mon,) studied this question.
synapsesocial.com/papers/69a765e4badf0bb9e87dae0b
https://doi.org/https://doi.org/10.1007/s42235-026-00842-9
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